Hebei Tianao Technology Co.,Ltd

CAS 98-92-0
Brief introduction:
Niacinamide, also known as nicotinamide, vitamin B3 or vitamin PP, is a water-soluble vitamin, belongs to the B group of vitamins, is a component of coenzyme I (nicotinamide adenine dinucleotide, NAD) and coenzyme II (nicotinamide adenine dinucleotide phosphate, NADP), in the human body these two coenzyme structures nicotinamide part has reversible hydrogenation and dehydrogenation characteristics, plays a role in biological oxidation, can promote tissue respiration, biological oxidation process and metabolism, to maintain normal tissues, especially skin, The integrity of the digestive tract and nervous system is of great significance. When deficient, pellagra is caused by the respiration and metabolism of cells, so this product is mainly used for the prevention and treatment of pellagra, stomatitis, glossitis, etc.
Chemical properties:
Niacinamide is a white needle-like crystalline or crystalline powder, odorless or slightly odorous, with a slightly bitter taste. The relative density is 1.4, and the melting point is 129-131 °C. 1g of this product is soluble in 1mL of water, 1.5mL of ethanol or 10mL of glycerol, insoluble in ether. A 10% aqueous solution has a pH of 6.5-7.5. It has weak moisture absorption. It is relatively stable, can resist acid, alkali and high temperature in dry air to light and heat, and generates niacin when heated in alkaline or acidic solution. Rats oral LD502.5-3.5g/kg, ADI value is not specified (ECC, 1990).
Apply:
Nicotinamide and niacin are used in most sonocombinations, and niacin is also produced in animals. When there is a lack of niacin and niacinamide in the body, you will get pellagra. Therefore, they prevent pellagra. They play a role in the metabolism of proteins and sugars to improve nutrition in humans and animals. In addition to being used as medicine, it is also widely used as food and feed additives.